Papers of March 2016

Welcome back to March’s papers of the month. Below are the papers we’re covering in the podcast. Make sure to take a look at the full papers yourself for a full critical appraisal.

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). Singer M. JAMA. 2016 Feb 23;315(8):801-10. doi: 10.1001/jama.2016.0287.

The Sepsis Trust certainly isn’t advocating their use yet, their statement can be found here; Interim statement regarding the new international consensus definitions of sepsis

Prehospital management and identification of sepsis by emergency medical services: a systematic review. Lane D. Emerg Med J. 2016 Feb 10. pii: emermed-2015-205261. doi: 10.1136/emermed-2015-205261. [Epub ahead of print]

Next up a related paper from the EMJ looking at sepsis but this time how easy it currently is to identify these patients;

Incidence of Adverse Events in Adults Undergoing Procedural Sedation in the Emergency Department: A Systematic Review and Meta-analysis. Bellolio MF. Acad Emerg Med. 2016 Feb;23(2):119-34. doi: 10.1111/acem.12875. Epub 2016 Jan 22.

Invasive versus conservative strategy in patients aged 80 years or older with non-ST-elevation myocardial infarction or unstable angina pectoris (After Eighty study): an open-label randomised controlled trial.Tegn N. Lancet. 2016 Jan 12. pii: S0140-6736(15)01166-6. doi: 10.1016/S0140-6736(15)01166-6. [Epub ahead of print]

Further Resources

FOAMcast; sepsis redefined

Stemlynsblog; Holy Smokes! Batman, the SOFA and the Latest Sepsis Definitions

  PulmCrit; Top 10 problems with the new sepsis definition