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NICE and JRCALC recommend the administration of TXA in GI bleeding?
A previous meta-analysis of the WOMAN trial and CRASH-2 showed that the effect of tranexamic acid on preventing deaths from bleeding was time dependant?
The total amount of TXA administered to patients in HALT-IT was the same as previously seen in CRASH-2 and CRASH-3?
HALT-IT showed no benefit in preventing death within 5 days from GI bleeding following administration of TXA?
Total thromboembolic events overall occurred at equal rates in both arms of the study?
Seizures were seen in equal proportions in both the TXA and placebo arms?