Papers of April 2022

RePHILL recruited prehospital patients who were experiencing haemorrhagic shock, or cardiac arrest, following trauma?

There was no difference seeing the primary outcome in RePHILL between the 2 groups i.e. those receiving packed red blood cells and Lyolplas vs this receiving 0.9% saline?

When looking in further depth into the composite primary outcome in RePHILL, the constituents of a failure to clear lactate and mortality both showed no difference between the two treatment arms?

Over-diagnosis can be defined as, ‘the labeling of a person with a disease or abnormal condition that would not have caused the person harm if left undiscovered, creating new diagnoses by medicalising ordinary life experiences, or expanding existing diagnoses by lowering thresholds or widening criteria without evidence of improved outcomes. Individuals derive no clinical benefits from over-diagnosis, although they may experience physical, psychological or financial harm.’ ?