Welcome back to the podcast!
In this episode of Roadside to Resus we’re going to take a look Anaphylaxis, which has been highlighted on a national level of concern as NICE state ‘many people do not receive optimal management following their acute anaphylactic reaction’.
Much of the problem lies within a lack of understanding of what actually constitutes an anaphylactic reaction and the knock on effect this has to the treatment provided.
In this episode we’ll explore the definition of anaphylaxis and the significant differences that can be seen in the presentation. We have a a think about the pathophysiology and reasons behind the variance in presentations and how this affects the importance of treatments available and their relative importance.
Anaphylaxis is known to have a a number of patients who have a biphasic reaction, it predicates the need to convey patients to hospital and a period of observation; however the frequency and severity of these biphasic reactions can help to inform this further and for that reason we take a look at the literature on it.
We’ve covered angioedema before in a separate episode, but we briefly cover the similarities and differences and how this affects management, but if you want to hear more about this have a listen to the full angioedema episode here.
Lastly we cover the follow up and management that these patients require.
We’d love to hear any comments or feedback you have and make sure to take a look at the references and resources below.
Enjoy!
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References
Life in the Fast Lane; Anaphylaxis
Immediate Hypersensitivity Reactions. Angel A. Stats Pearls. 2020
The pathophysiology of anaphylaxis. Laurent L. J Allergy Clin Immunol. 2018
Fatal asthma or anaphylaxis? J Rainbow. Emerg Med J. 2002
Anaphylaxis. Kim H. Allergy, Asthma & Clinical Immunology. 2011
Anaphylaxis. Fischer. Allergy Asthma Clin Immunol. 2018
Immediate Hypersensitivity Reactions. Angel A. Stats Pearls. 2020
The pathophysiology of anaphylaxis. Laurent L. J Allergy Clin Immunol. 2018.
Fatal asthma or anaphylaxis? J Rainbow. Emerg Med J. 2002
Anaphylaxis. Kim H. Allergy, Asthma & Clinical Immunology. 2011
Anaphylaxis. Fischer. Allergy Asthma Clin Immunol. 2018
Fatal anaphylaxis in the UK, 1992-2001. Novartis Foundation Symposium. Pumphrey. 2004
Time to revisit the definition and clinical criteria for anaphylaxis? Paul J. Turner. World Allergy Organ J. 2019
Fatal anaphylaxis in the UK, 1992-2001. Novartis Foundation Symposium. Pumphrey. 2004